1-(Cyclopropylcarbonyl)piperazine
1-(Cyclopropylcarbonyl)piperazine (CAS: 59878-57-8), with the molecular formula C8H14N2O and a molecular weight of 154.21 g/mol, is a valuable heterocyclic building block. Its structure features a piperazine ring acylated with a cyclopropylcarbonyl group. This compound serves as a versatile intermediate in chemical synthesis, particularly for the development of novel pharmaceutical agents and complex organic molecules. It is supplied by Tech Serve Solutions with a typical assay of 97%.

Pharmaceutical Intermediate
This compound is widely employed in the synthesis of active pharmaceutical ingredients (APIs). Its unique structure allows for the introduction of the cyclopropylcarbonylpiperazine moiety into drug candidates, potentially influencing their pharmacological properties.
Organic Synthesis Building Block
As a functionalised piperazine derivative, it is a key reagent in complex organic synthesis. It enables the construction of larger molecules with defined structural features for research and development purposes.
Research and Development
Utilised in academic and industrial research labs for exploring new chemical reactions and creating novel compounds. Its availability facilitates advancements in medicinal chemistry and materials science.
| Molecular weight | 154.21 |
|---|---|
| Empirical formula | C8H14N2O |
| Assay | 97% |
| Boiling point | 120 °C/0.15 mmHg |
| Density | 1.087 g/mL at 25 °C |
| Refractive index | n20/D 1.524 |


Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(Cyclopropylcarbonyl)piperazine used for?
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1-(Cyclopropylcarbonyl)piperazine (CAS: 59878-57-8) is primarily used as a versatile building block in organic synthesis, especially in the development of pharmaceutical intermediates and novel chemical entities.
What is the CAS number and formula for 1-(Cyclopropylcarbonyl)piperazine?
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The CAS number for 1-(Cyclopropylcarbonyl)piperazine is 59878-57-8, and its molecular formula is C8H14N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(Cyclopropylcarbonyl)piperazine with a typical assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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This compound carries a Danger signal word and is classified with hazards H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Ensure adequate ventilation and avoid breathing dust or vapours.
How is 1-(Cyclopropylcarbonyl)piperazine packed and exported?
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Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to all necessary safety and regulatory requirements for transportation.
How can I request a sample or quote for 1-(Cyclopropylcarbonyl)piperazine?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (59878-57-8).
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