1-Bromo-3-chloro-2,2-dimethoxypropane
1-Bromo-3-chloro-2,2-dimethoxypropane (CAS: 22089-54-9), also known by its linear formula ClCH2C(OCH3)2CH2Br, is an organic compound with a molecular weight of 217.49 g/mol. As a functionalized acetal and alkyl halide, it serves as a valuable building block in organic synthesis. Its distinct reactive sites allow for diverse chemical transformations, making it a key intermediate in the preparation of more complex molecules for research and development purposes.
- Synonyms
- ClCH2C(OCH3)2CH2Br

Organic Synthesis Intermediate
This compound acts as a versatile intermediate in the synthesis of various organic molecules. The presence of both a bromine and a chlorine atom, along with the acetal functional group, allows for selective reactions and the introduction of specific structural motifs.
Building Block for Heterocycles
1-Bromo-3-chloro-2,2-dimethoxypropane can be employed in the construction of heterocyclic compounds. Its difunctional nature is amenable to cyclization reactions, forming ring systems relevant in medicinal chemistry and materials science.
Reagent in Specialty Chemicals
Used in the development and manufacturing of specialty chemicals, this compound contributes to the creation of novel materials and complex organic structures for advanced research applications.
| Molecular weight | 217.49 |
|---|---|
| Linear formula | ClCH2C(OCH3)2CH2Br |
| Assay | 95% |
| Melting point | 69-71 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-3-chloro-2,2-dimethoxypropane used for?
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1-Bromo-3-chloro-2,2-dimethoxypropane is primarily used as a versatile building block and intermediate in organic synthesis, particularly for the construction of complex organic molecules and heterocyclic compounds.
What is the CAS number and formula for 1-Bromo-3-chloro-2,2-dimethoxypropane?
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The CAS number is 22089-54-9 and the linear formula is ClCH2C(OCH3)2CH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-3-chloro-2,2-dimethoxypropane with an assay of 95%. This is a technical grade suitable for research and synthesis; TSS does not represent it as USP, BP, or EP grade.
What are the safety considerations for handling 1-Bromo-3-chloro-2,2-dimethoxypropane?
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This compound is classified with GHS07 and carries a Warning signal word. It is harmful if swallowed (H302), harmful in contact with skin (H312), causes skin irritation (H315), causes serious eye irritation (H319), and harmful if inhaled (H332), potentially causing respiratory irritation (H335). Appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves must be worn. Ensure adequate ventilation.
How is 1-Bromo-3-chloro-2,2-dimethoxypropane packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all relevant shipping regulations. Specific packaging details are available upon request.
How can I request a sample or quote for 1-Bromo-3-chloro-2,2-dimethoxypropane?
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To request a sample or a quote, please contact the TSS sales department via the website or direct email, providing your specific requirements and shipping information.
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