1-Benzylpiperazine
1-Benzylpiperazine (CAS: 2759-28-6), with the molecular formula C11H16N2 and a molecular weight of 176.26 g/mol, is a chemical compound utilized in various research and synthesis applications. It serves as a building block in organic synthesis, particularly in the development of bioactive molecules and heterocyclic compounds. This chemical is supplied by Tech Serve Solutions for research and development purposes.

Research in Acetylcholinesterase Inhibition
1-Benzylpiperazine has been employed in studies investigating the inhibitory effects of complex organic molecules, such as camptothecin derivatives, on acetylcholinesterase enzymes. This research contributes to understanding enzyme kinetics and potential therapeutic targets.
Organic Synthesis Intermediate
As a versatile building block, 1-Benzylpiperazine is valuable in the synthesis of more complex organic molecules. Its structure allows for further functionalisation, making it useful in creating novel compounds within heterocyclic chemistry and medicinal chemistry research.
Development of Bioactive Small Molecules
The compound serves as a precursor in the creation of small molecules with potential biological activity. Its incorporation into molecular structures aids in the exploration of new chemical entities for biological screening and drug discovery processes.
| Molecular weight | 176.26 |
|---|---|
| Empirical formula | C11H16N2 |
| Assay | ≥97.0% (GC) |
| Density | 1.014 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.547(lit.)n20/D 1.547 |
| Application | 1-Benzylpiperazine was used to study the inhibition of various acetylcholinesterases by 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin and related compounds1. |
| Melting point | 17-20 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 123 °C / 253.4 °F |
| Transport (UN / ADR) | UN 3267 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule I |
|---|---|
| Gene Information | rat ... Htr2a(29595), Htr2c(25187) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Benzylpiperazine used for?
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1-Benzylpiperazine is used as a building block in organic synthesis, particularly in the development of bioactive small molecules and heterocyclic compounds, and in research related to enzyme inhibition.
What is the CAS number and formula for 1-Benzylpiperazine?
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The CAS number for 1-Benzylpiperazine is 2759-28-6, and its empirical formula is C11H16N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Benzylpiperazine with a purity of ≥97.0% (GC). This product is intended for research and laboratory use, and TSS does not represent it as USP, BP, or EP grade.
How should 1-Benzylpiperazine be handled safely?
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1-Benzylpiperazine is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including faceshields, full-face respirators, gloves, and goggles, is essential. Handle in a well-ventilated area and refer to the Safety Data Sheet for comprehensive handling instructions.
Is 1-Benzylpiperazine a controlled substance?
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Data indicates 1-Benzylpiperazine is listed under USDEA Schedule I. Please consult relevant local regulations for specific handling and possession requirements.
How is 1-Benzylpiperazine packed and shipped?
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1-Benzylpiperazine is packed and shipped in compliance with relevant regulations, including UN 3267 8 / PGII classification for transport.
How can I request a sample or quote for 1-Benzylpiperazine?
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To request a sample or a quote for 1-Benzylpiperazine, please contact the Tech Serve Solutions sales team through our official website or listed contact information.
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