1-Benzyl-4-cyano-4-hydroxypiperidine hydrochloride
1-Benzyl-4-cyano-4-hydroxypiperidine hydrochloride (CAS: 6094-60-6), with the empirical formula C13H16N2O · HCl and a molecular weight of 252.74, is a valuable heterocyclic building block. This compound serves as a key intermediate in chemical synthesis, particularly within the pharmaceutical industry, aiding in the construction of complex molecular architectures. Its utility stems from the piperidine core and functional groups, enabling diverse synthetic transformations. It is supplied with an assay of 97%.
- IUPAC
- 1-Benzyl-4-hydroxyisonipecotonitrile hydrochloride

Pharmaceutical Intermediate
This piperidine derivative is frequently employed as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structure allows for modification and incorporation into drug candidates targeting various therapeutic areas.
Organic Synthesis Reagent
As a functionalized heterocyclic building block, it is utilized in a wide range of organic synthesis research and development. It facilitates the creation of novel compounds and the exploration of new chemical entities.
Research and Development
Researchers in academic and industrial settings use 1-Benzyl-4-cyano-4-hydroxypiperidine hydrochloride for developing new synthetic methodologies and exploring novel chemical structures. Its specific functionalities make it a useful tool for targeted synthesis projects.
| Molecular weight | 252.74 |
|---|---|
| Empirical formula | C13H16N2O · HCl |
| Assay | 97% |
| Melting point | 175-177 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Benzyl-4-cyano-4-hydroxypiperidine hydrochloride used for?
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This compound is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceutical compounds and other complex molecules.
What are the CAS number and formula for this product?
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The CAS number is 6094-60-6, and the empirical formula is C13H16N2O · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Benzyl-4-cyano-4-hydroxypiperidine hydrochloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the main safety hazards associated with this chemical?
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This compound is harmful if swallowed, in contact with skin, or if inhaled. It also causes skin and serious eye irritation, and may cause respiratory irritation. Always handle with appropriate personal protective equipment, including a dust mask, eyeshields, and gloves.
Can this chemical be exported internationally?
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Yes, Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, including 1-Benzyl-4-cyano-4-hydroxypiperidine hydrochloride, adhering to all relevant shipping regulations.
How can I request a sample or a quote?
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To request a sample or obtain a quotation for 1-Benzyl-4-cyano-4-hydroxypiperidine hydrochloride, please contact our sales team through the website or by phone, providing your specific requirements.
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