1-Aminopiperidine
1-Aminopiperidine (CAS: 2213-43-6), with the chemical formula C5H12N2 and a molecular weight of 100.16 g/mol, is a heterocyclic amine. This compound serves as a valuable building block in organic synthesis, particularly in the development of novel chemical entities. It is employed in the creation of various complex molecules, including pharmaceutical intermediates and research chemicals, contributing to advancements in medicinal chemistry and materials science.
- IUPAC
- Pentamethylenehydrazine,Piperidin-1-ylamine
- Synonyms
- PentamethylenehydrazinePiperidin-1-ylamine

CB1 Cannabinoid Receptor Ligands
1-Aminopiperidine is utilised as a reactant in the synthesis of specific CB1 cannabinoid receptor ligands, which are important targets in pharmacological research.
Hydrazone Derivatives
This compound is a precursor in the preparation of various hydrazone derivatives, enabling the formation of new chemical structures with diverse potential applications.
Tetrahydronaphthalene Synthesis
It functions as a reactant in the synthesis of tetrahydronaphthalene derivatives that have demonstrated effects on proliferation and nitric oxide production in activated macrophage cell lines.
Phosphorus(V) Hydrazines
1-Aminopiperidine serves as a key intermediate in the synthesis of phosphorus(V) hydrazines, contributing to the field of organophosphorus chemistry.
| Molecular weight | 100.16 |
|---|---|
| Empirical formula | C5H12N2 |
| Assay | 97% |
| Boiling point | 146 °C/730 mmHg(lit.) |
| Density | 0.928 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.475(lit.) |
| Application | Reactant for synthesis of:• CB1 cannabinoid receptor ligands1†• Hydrazones2†• Tetrahydronaphthalene derivatives affecting proliferation and nitric oxide production in LPS activated RAW 264.7 macrophages3• Phosphorus(V) hydrazines4 |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 36 °C / 96.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Aminopiperidine primarily used for?
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1-Aminopiperidine is used as a reactant in the synthesis of CB1 cannabinoid receptor ligands, hydrazones, tetrahydronaphthalene derivatives, and phosphorus(V) hydrazines.
What is the CAS number and chemical formula for 1-Aminopiperidine?
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The CAS number is 2213-43-6 and the chemical formula is C5H12N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Aminopiperidine with an assay of 97%. This product is not represented as USP, BP, or EP grade.
How should 1-Aminopiperidine be handled safely?
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1-Aminopiperidine is a flammable liquid and vapour (H226) and is irritating to skin, eyes, and respiratory tract (H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area, away from ignition sources.
Is 1-Aminopiperidine available for international export?
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Yes, Tech Serve Solutions, a specialist global supplier and exporter, offers 1-Aminopiperidine for international export.
How can I request a quote or sample of 1-Aminopiperidine?
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Please contact our sales team via the website or by telephone to request a quote or sample of 1-Aminopiperidine.
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