1,9-Dideoxyforskolin from Coleus forskohlii

CAS 64657-18-7C22H34O5Cell Biology

1,9-Dideoxyforskolin (CAS: 64657-18-7) is a diterpenoid derived from Coleus forskohlii. With a molecular weight of 378.50 g/mol and empirical formula C22H34O5, this compound is primarily recognised for its utility as a negative control in research involving forskolin and adenylyl cyclase activation. It is supplied as a white to off-white solid.

IUPAC: 7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one
Synonyms: C22H34O5

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1,9-Dideoxyforskolin from Coleus forskohlii (C22H34O5) — chemical structure, CAS 64657-18-7; Life Science, fine chemical supplied by Tech Serve Solutions

Adenylyl Cyclase ActivatorsBioactive Small MoleculesCell BiologyCyclic Nucleotide MetabolismD-DIF

01 /Applications

Adenylyl Cyclase Research

Serves as a critical negative control in studies investigating the activation of adenylyl cyclase, helping to delineate the specific effects of forskolin and related compounds.

Cell Signalling Studies

A valuable tool in cell biology and neuroscience research for modulating cyclic nucleotide metabolism and understanding G protein-coupled receptor pathways.

Biochemical Assays

Utilised in biochemical assays to provide a baseline or control condition when examining enzyme activity, particularly in the context of cyclic AMP production.

02 /Properties

Molecular weight	378.50
Empirical formula	C22H34O5
Assay	≥97%
Form	solid
Colour	white to off-white
Solubility	methanol: soluble28 mg/mL(lit.)DMSO: soluble3 mg/mL(lit.)chloroform: soluble50 mg/mLethanol: soluble6.6 mg/mL(lit.)dilute aqueous acid and base: insoluble(lit.)
Optical activity	[α]26/D +93.6°, c = 6.12 in chloroform(lit.)
Storage temperature	−20°C
Application	Useful as a negative control for forskolin.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

64657-18-7

MDL number

MFCD00082318

PubChem substance

24893774

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1,9-Dideoxyforskolin used for?

1,9-Dideoxyforskolin (CAS: 64657-18-7) is primarily used as a negative control in research, particularly for studies involving forskolin and adenylyl cyclase activation.

What are the CAS number and formula for 1,9-Dideoxyforskolin?

The CAS number for 1,9-Dideoxyforskolin is 64657-18-7. Its empirical formula is C22H34O5, and its molecular weight is 378.50 g/mol.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1,9-Dideoxyforskolin with a purity of ≥97%. This is a research-grade chemical, and TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.

What safety precautions should be taken when handling 1,9-Dideoxyforskolin?

When handling 1,9-Dideoxyforskolin, it is essential to use personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard.