1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane
1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane (CAS 214078-92-9) is a cyclic tetraamine with the molecular formula C12H28N4 and a molecular weight of 228.38 g/mol. This compound serves as a key building block in chemical synthesis. Its applications include facilitating ferromagnetic coupling in metal complexes and acting as a precursor for developing novel platinum(II) complexes with potential antitumor activity and fluoroionophores for metal ion detection.
- IUPAC
- 1,8-Dimethylcyclam
- Synonyms
- 1,8-Dimethylcyclam8,11-tetraazacyclotetradecane

Precursor for Metal Complexes
This compound is utilised as a reactant in the synthesis of metal complexes, such as those involving copper(II) and nickel(II), enabling studies in ferromagnetic coupling.
Development of Antitumor Agents
It serves as a building block in the preparation of cyclam-bridged dinuclear platinum(II) complexes, which are investigated for their potential as antitumor agents.
Fluoroionophore Synthesis
The compound is employed in the preparation of dimethylcyclam-based fluoroionophores, designed to exhibit selective signalling behaviours for ions like Hg2+ and Cd2+.
| Molecular weight | 228.38 |
|---|---|
| Empirical formula | C12H28N4 |
| Boiling point | 98-99 °C(lit.) |
| Density | 0.944 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4940(lit.) |
| Application | Reactant for:• Ferromagnetic coupling of copper(II) and nickel(II) complexes1• Preparation of cyclam bridged dinuclear platinum(II) complex as an antitumor agent2• Preparation of dimethylcyclam based fluoroionophore having Hg2+- and Cd2+-selective signaling behaviors3 |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane used for?
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1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane (CAS 214078-92-9) is used as a building block in chemical synthesis, including the preparation of metal complexes, potential antitumor agents, and fluoroionophores.
What is the CAS number and formula for 1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane?
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The CAS number is 214078-92-9 and the empirical formula is C12H28N4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and grade available may vary; please consult the product specifications for details. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.
How should 1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. Use a half-mask respirator. Refer to the safety data sheet for comprehensive handling and hazard information. It has a flash point of 90 °C (194 °F) and is classified under NA 1993 / PGIII.
Is 1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane.
How can I request a quote or sample?
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To request a quote or a sample of 1,8-Dimethyl-1,4,8,11-tetraazacyclotetradecane, please visit the Tech Serve Solutions website or contact our sales team directly.
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