1,5-Diiodopentane
1,5-Diiodopentane (CAS 628-77-3) is a difunctional alkyl diiodide with the linear formula I(CH2)5I and a molecular weight of 323.94. Tech Serve Solutions supplies it at 97% assay, typically stabilised with copper. A dense liquid (2.177 g/mL) of refractive index n20/D 1.6002, it is used as a five-carbon building block in chemical synthesis, where its two reactive primary iodides serve in alkylation, cross-linking and the assembly of cyclic and organometallic structures.
- Synonyms
- 1,5-DiiodopentaneI(CH2)5IPentamethylene diiodide1,5-Pentanediyl diiodidepentane, 1,5-diiodo-CAS 628-77-3

Five-carbon bis-alkylating building block
The two terminal primary iodides make 1,5-diiodopentane an effective bis-alkylating reagent for introducing a pentamethylene (C5) bridge between nucleophiles. It is widely used in organic synthesis for chain extension and ring construction.
Cross-linking reagent
It has been used as a cross-linking reagent, for example to investigate layer-by-layer films of bioreducible poly(2-dimethylaminoethyl methacrylate) and DNA. The reactive diiodide forms covalent links between pendant amine groups.
Organometallic complex synthesis
1,5-Diiodopentane has been used in the preparation of (iodoalkylaminocarbene)tungsten complexes. It serves as a halogenated precursor for installing iodoalkyl substituents in organometallic chemistry.
Research and laboratory reagent
As an organic building block in the halogenated hydrocarbons class, it supports method development and small-scale exploratory synthesis in research laboratories where a defined alpha,omega-diiodoalkane is required.
| Molecular weight | 323.94 |
|---|---|
| Linear formula | I(CH2)5I |
| Assay | 97% |
| Boiling point | 101-102 °C/3 mmHg(lit.) |
| Density | 2.177 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.6002(lit.) |
| Contains / stabiliser | copper as stabilizer |
| Application | 1,5-Diiodopentane has been used:• as crosslinking reagent, to investigate the cross-linking layer-by-layer films of bioreducible poly(2-dimethylaminoethyl methacrylate) and DNA1• in preparation of (iodoalkylaminocarbene)tungsten complexes2 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,5-Diiodopentane used for?
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1,5-Diiodopentane is used primarily as a five-carbon difunctional building block in chemical synthesis. Its two reactive primary iodides make it suitable for bis-alkylation, as a cross-linking reagent, and as a precursor in organometallic chemistry, including the preparation of iodoalkylaminocarbene tungsten complexes.
What is the CAS number and molecular formula of 1,5-Diiodopentane?
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The CAS number is 628-77-3 and the linear formula is I(CH2)5I, corresponding to a molecular weight of 323.94. Its EC number is 211-054-1 and the MDL number is MFCD00001101.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,5-Diiodopentane at 97% assay, typically containing copper as a stabiliser. This is a research and technical grade material; we do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis is provided with each batch.
What are the safety and handling precautions for 1,5-Diiodopentane?
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It carries GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Use eye protection, gloves and suitable respiratory protection, work with adequate ventilation, and consult the SDS before use. Its water hazard class is WGK 3.
How is 1,5-Diiodopentane packed, shipped and exported?
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It is packed as a liquid in tightly closed, light-protected containers appropriate to the order quantity, with full labelling and documentation. Tech Serve Solutions exports worldwide in compliance with applicable transport and customs requirements; packaging sizes can be tailored to laboratory or bulk needs on request.
How do I request a sample or quote?
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Send us your required quantity, purity and destination and our team will respond with availability, lead time and a quotation. Tech Serve Solutions has supplied fine chemicals and reagents internationally since 1998.
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