1-[4-(Trifluoromethyl)benzyl]piperazine

CAS 107890-32-4C12H15F3N2Chemical Synthesis

1-"4-(Trifluoromethyl)benzyl]piperazine" (CAS: 107890-32-4), a fluorinated organic compound with the formula C12H15F3N2 and a molecular weight of 244.26 g/mol. This versatile building block features a trifluoromethyl-substituted benzyl group attached to a piperazine ring. It serves as a valuable intermediate in the synthesis of complex molecules, particularly within the pharmaceutical and agrochemical sectors. Its unique structure allows for diverse chemical modifications.

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1-[4-(Trifluoromethyl)benzyl]piperazine (C12H15F3N2) — chemical structure, CAS 107890-32-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC12Chemical SynthesisHeterocyclic Building BlocksPiperazines

01 /Applications

Pharmaceutical Synthesis

Utilised as a key intermediate in the development of active pharmaceutical ingredients (APIs). The trifluoromethyl group and piperazine moiety offer sites for further chemical elaboration in drug discovery programs.

Agrochemical Research

Serves as a building block for the synthesis of novel agrochemical compounds. Its structural features can be incorporated into pesticides, herbicides, or fungicides.

Organic Synthesis

A useful reagent in general organic synthesis, enabling the introduction of the (trifluoromethyl)benzylpiperazine fragment into various molecular architectures.

Material Science

Potentially used in the development of novel materials where its specific chemical properties can be leveraged for functional applications.

02 /Properties

Molecular weight	244.26
Empirical formula	C12H15F3N2
Assay	97%
Boiling point	88-89 °C/0.02 mmHg
Density	1.239 g/mL at 25 °C
Refractive index	n20/D 1.491

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P301IF SWALLOWED
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Flash point	>110 °C / >230 °F
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	2
Hazard codes (EU)	Xn
Risk statements (R)	22-36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

107890-32-4

MDL number

MFCD03407490

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-[4-(Trifluoromethyl)benzyl]piperazine used for?

1-[4-(Trifluoromethyl)benzyl]piperazine (CAS: 107890-32-4) is primarily used as a building block and intermediate in organic synthesis, particularly for pharmaceutical and agrochemical research and development.

What are the CAS number and formula for this chemical?

The CAS number is 107890-32-4, and the molecular formula is C12H15F3N2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

How should 1-[4-(Trifluoromethyl)benzyl]piperazine be handled?

This compound is classified as Danger, with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves, in a well-ventilated area.