1,4-Dioxa-8-azaspiro[4.5]decane
1,4-Dioxa-8-azaspiro[4.5]decane (CAS: 177-11-7) is a heterocyclic organic compound with the molecular formula C7H13NO2 and a molecular weight of 143.18 g/mol. This spirocyclic amine derivative, often referred to as 4-piperidone ethylene acetal, serves as a valuable building block in chemical synthesis. Its structure lends itself to applications in the preparation of more complex molecules, particularly within the realm of heterocyclic chemistry.
- IUPAC
- 4-Piperidone ethylene acetal
- Synonyms
- 4-Piperidone ethylene acetal1,4-Dioxa-8-azaspiro[4.5]decane, 8-Azaspiro[4.5]decane-1,4-diol ethylene acetal8-Aza-1,4-dioxaspiro[4.5]decane
![1,4-Dioxa-8-azaspiro[4.5]decane (C7H13NO2) — chemical structure, CAS 177-11-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F177-11-7.png&w=3840&q=75)
Synthesis of Spirocyclotriphosphazenes
1,4-Dioxa-8-azaspiro[4.5]decane has been utilised as a precursor in the synthesis of novel 1,4-dioxa-8-azaspiro[4,5] deca spirocyclotriphosphazene derivatives. This highlights its role in constructing complex cage-like phosphorus-nitrogen ring systems.
Heterocyclic Building Block
As a functionalised spirocyclic compound, it is employed as a versatile building block in organic synthesis. Its unique structure allows for the introduction of specific functionalities in the development of new chemical entities.
Chemical Synthesis Intermediate
The compound functions as an intermediate in multi-step synthetic pathways. Its presence allows chemists to achieve target molecules that may be difficult to access through other routes.
| Molecular weight | 143.18 |
|---|---|
| Empirical formula | C7H13NO2 |
| Assay | 98% |
| Boiling point | 108-111 °C/26 mmHg(lit.) |
| Density | 1.117 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.4819(lit.) |
| Application | 1,4-Dioxa-8-azaspiro[4.5]decane was used in the synthesis of 1,4-dioxa-8-azaspiro [4,5] deca spirocyclotriphosphazenes1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 81 °C / 177.8 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Dioxa-8-azaspiro[4.5]decane used for?
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1,4-Dioxa-8-azaspiro[4.5]decane is used as a building block in chemical synthesis, particularly noted for its application in the preparation of spirocyclotriphosphazenes and other heterocyclic compounds.
What are the CAS number and molecular formula for 1,4-Dioxa-8-azaspiro[4.5]decane?
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The CAS number for 1,4-Dioxa-8-azaspiro[4.5]decane is 177-11-7 and its molecular formula is C7H13NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Dioxa-8-azaspiro[4.5]decane with a minimum assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 1,4-Dioxa-8-azaspiro[4.5]decane be handled safely?
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1,4-Dioxa-8-azaspiro[4.5]decane is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment including eyeshields and gloves, and ensure adequate ventilation or use a suitable respirator.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1,4-Dioxa-8-azaspiro[4.5]decane.
How can I request a sample or quote?
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To request a sample or a quote for 1,4-Dioxa-8-azaspiro[4.5]decane, please contact our sales team through the website or by phone.
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