1,4-Dichlorophthalazine
1,4-Dichlorophthalazine (CAS: 4752-10-7) is a halogenated heterocyclic organic compound with the molecular formula C8H4Cl2N2 and a molecular weight of 199.04 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly within medicinal chemistry and the development of novel materials. Its reactive nature allows for versatile functionalisation, making it a key intermediate in creating complex molecular architectures.
- Synonyms
- C8H4Cl2N2
Medicinal Chemistry Intermediate
1,4-Dichlorophthalazine is frequently employed as a starting reagent in the synthesis of diverse pharmaceutical candidates. It has been used in the preparation of 4-aryl-1-(4-methylpiperazin-1-yl)phthalazine derivatives, contributing to the exploration of new therapeutic agents.
Polymer-Supported Ligand Synthesis
The compound acts as a coupling reagent in the creation of novel soluble polymer-bound ligands. This application is crucial for developing advanced materials used in catalysis and separation technologies.
Heterocyclic Synthesis
As a halogenated heterocycle, 1,4-Dichlorophthalazine is a fundamental building block for constructing more complex heterocyclic systems. Its utility spans various organic synthesis pathways requiring pyridazine scaffolds.
| Molecular weight | 199.04 |
|---|---|
| Empirical formula | C8H4Cl2N2 |
| Assay | 95% |
| Storage temperature | −20°C |
| Application | 1,4-Dichlorophthalazine was used as starting reagent in the synthesis of series of 4-aryl-1-(4-methylpiperazin-1-yl)phthalazines1. It was used as coupling reagent in the synthesis of novel soluble polymer-bound ligand2. It was often used as building block in medicinal chemistry synthesis3,4. |
| Melting point | 160-162 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Dichlorophthalazine used for?
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1,4-Dichlorophthalazine is used as a starting reagent in the synthesis of 4-aryl-1-(4-methylpiperazin-1-yl)phthalazines, as a coupling reagent in the synthesis of novel soluble polymer-bound ligands, and as a building block in medicinal chemistry and general chemical synthesis.
What is the CAS number and molecular formula for 1,4-Dichlorophthalazine?
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The CAS number is 4752-10-7 and the molecular formula is C8H4Cl2N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Dichlorophthalazine with an assay of 95%. TSS does not represent this product as USP, EP, BP, or other pharmacopoeial grades.
How should 1,4-Dichlorophthalazine be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C to maintain stability. The compound has a GHS hazard classification of 3 for WGK Germany.
Is 1,4-Dichlorophthalazine suitable for human or animal consumption?
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This compound is intended for laboratory research and chemical synthesis purposes only. It is not suitable for human or animal consumption or for use in pharmaceutical products unless further processed and verified.
How can I request a quote or sample of 1,4-Dichlorophthalazine?
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To request a quote or sample, please contact our sales department via the website or direct email, providing your contact details and the quantity required.
How is 1,4-Dichlorophthalazine packed and shipped internationally?
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1,4-Dichlorophthalazine is carefully packed according to international shipping regulations for chemical compounds. We are experienced exporters and can ship globally to qualified research institutions and industrial clients.
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