1-(4-Bromobenzyl)piperazine
1-(4-Bromobenzyl)piperazine (CAS 91345-62-9; C11H15BrN2; molar mass 255.15 g/mol) is a halogenated piperazine building block supplied by Tech Serve Solutions at 97% assay. The molecule combines a 4-bromobenzyl group with a secondary piperazine nitrogen, giving a versatile bifunctional scaffold for chemical synthesis. It is used chiefly as a research-grade intermediate in medicinal chemistry and the preparation of heterocyclic and pharmaceutical-intermediate libraries. It is a UK Home Office Schedule 1 controlled substance.
- Synonyms
- 1-(4-Bromobenzyl)piperazine1-[(4-Bromophenyl)methyl]piperazine4-BromobenzylpiperazineCAS 91345-62-9MFCD02177416
Heterocyclic building block
Serves as a bifunctional piperazine scaffold for chemical synthesis, where the free secondary amine offers a convenient handle for N-functionalisation, acylation and reductive amination.
Pharmaceutical-intermediate research
Used as a research-grade intermediate in medicinal chemistry programmes that explore substituted benzylpiperazine motifs. Tech Serve Solutions supplies it strictly for lawful research and manufacturing use.
Cross-coupling substrate
The aryl bromide allows participation in palladium-catalysed cross-coupling chemistry, such as Suzuki, Heck and Buchwald-Hartwig reactions, enabling further elaboration of the aromatic ring.
Library and scaffold synthesis
Its halogenated-heterocycle character makes it suitable for building focused compound libraries and for assembling more complex piperazine-containing structures in discovery chemistry.
| Molecular weight | 255.15 |
|---|---|
| Empirical formula | C11H15BrN2 |
| Assay | 97% |
| Boiling point | 112-116 °C/0.3 mmHg(lit.) |
| Melting point | 56-62 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259 8/PG 3 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | Home Office Schedule 1 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Bromobenzyl)piperazine used for?
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It is used mainly as a research-grade building block and intermediate in chemical synthesis and medicinal chemistry. The combination of a reactive secondary piperazine nitrogen and an aryl bromide makes it useful for N-functionalisation and palladium-catalysed cross-coupling. It is supplied only for lawful research and manufacturing purposes.
What is the CAS number and molecular formula of 1-(4-Bromobenzyl)piperazine?
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The CAS number is 91345-62-9 and the molecular formula is C11H15BrN2, with a molecular weight of 255.15 g/mol. The MDL number is MFCD02177416.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(4-Bromobenzyl)piperazine at 97% assay as a research/technical-grade building block. We do not represent it as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each consignment.
Is 1-(4-Bromobenzyl)piperazine a controlled substance?
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Yes. The supplied data classes it as a UK Home Office Schedule 1 controlled substance. Purchase, import, export and possession may require appropriate licences and documentation. Customers must confirm and meet the controlled-substance requirements applicable in their jurisdiction before ordering.
What are the safety and handling precautions?
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It is classified GHS05 and GHS07, signal word Danger, with hazard statements H302 (harmful if swallowed) and H314 (causes severe skin burns and eye damage). Avoid contact with skin and eyes, avoid ingestion, and use eye and face protection, suitable gloves and respiratory protection. Always consult the Safety Data Sheet before use.
How is 1-(4-Bromobenzyl)piperazine packed, shipped and exported?
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It is packed in suitable laboratory or bulk containers and shipped as a Class 8 corrosive material under UN 3259, packing group III, with WGK 2 (water hazard class). As a controlled substance, export is handled in line with the relevant licensing and dangerous-goods regulations, with full documentation.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, together with any controlled-substance licence details. Our team will confirm availability, regulatory documentation and lead time and respond with a formal quotation.
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