1-(3-Methoxyphenyl)piperazine
1-(3-Methoxyphenyl)piperazine (CAS 16015-71-7) is an aryl-substituted piperazine with the molecular formula C11H16N2O and a molecular weight of 192.26 g/mol. Supplied by Tech Serve Solutions as a research-grade reagent of around 95% assay, it is a versatile heterocyclic building block. The 3-methoxyphenyl piperazine scaffold is widely used in medicinal-chemistry synthesis and is documented as a ligand at the serotonin 5-HT1A receptor in pharmacological research.
- Synonyms
- 1-(3-Methoxyphenyl)piperazine3-Methoxyphenylpiperazine1-(m-Methoxyphenyl)piperazine1-(3-Methoxyphenyl)piperazine free basem-MPP
Pharmaceutical and medicinal-chemistry intermediate
Serves as a key arylpiperazine building block in the synthesis of pharmaceutical intermediates and candidate molecules. The free secondary amine on the piperazine ring is a convenient handle for N-alkylation, N-acylation and reductive amination.
Heterocyclic building block for organic synthesis
Used in research-scale chemical synthesis to introduce the substituted piperazine motif into more complex structures. It is a common scaffold in fragment- and library-based discovery chemistry.
Serotonergic receptor research
The 3-methoxyphenylpiperazine scaffold is documented in the literature as a ligand for serotonin (5-HT1A) receptors, making it of interest as a reference compound and starting point in neuropharmacology studies.
Reference and laboratory reagent
Functions as a laboratory reagent and characterised reference material for method development, analytical work and structure-activity exploration around the arylpiperazine class.
| Molecular weight | 192.26 |
|---|---|
| Empirical formula | C11H16N2O |
| Assay | 95% |
| Boiling point | 150 °C/0.5 mmHg(lit.) |
| Density | 1.114 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5815(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 3267 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Htr1a(24473) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Methoxyphenyl)piperazine used for?
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It is used chiefly as a heterocyclic building block and pharmaceutical intermediate in research-scale organic synthesis. The arylpiperazine scaffold is a common starting point in medicinal chemistry and is documented as a ligand at the serotonin 5-HT1A receptor in pharmacological research.
What is the CAS number and molecular formula of 1-(3-Methoxyphenyl)piperazine?
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The CAS number is 16015-71-7 and the molecular formula is C11H16N2O, with a molecular weight of 192.26 g/mol. The MDL number is MFCD00040733 and the EC number is 240-154-8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(3-Methoxyphenyl)piperazine as a research/technical-grade reagent with a typical assay of approximately 95%. We do not represent it as a USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch.
What are the safety and handling requirements?
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It is classified GHS05, signal word Danger, with hazard statement H314 (causes severe skin burns and eye damage). Handle only with suitable gloves, goggles or faceshield and respiratory protection, avoid contact with skin and eyes, and consult the SDS before use. Refer to the precautionary statements P280, P305+P351+P338 and P310.
How is 1-(3-Methoxyphenyl)piperazine packed, shipped and exported?
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It is packed in suitably sealed, corrosion-resistant containers with sizes to suit laboratory and bulk research requirements, each clearly labelled with batch details. As a corrosive material it is classified for transport as UN 3267, Class 8, Packing Group III, and is shipped in compliance with applicable dangerous-goods regulations for export worldwide.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, documentation and a quotation. Samples can be arranged for qualification subject to the product's hazard classification and shipping requirements.
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