1-(3-Formylphenyl)piperazine
1-(3-Formylphenyl)piperazine (CAS 870703-56-3; C11H14N2O; molar mass 190.24 g/mol), also known as 3-(piperazin-1-yl)benzaldehyde, is a bifunctional heterocyclic building block. It combines an aromatic aldehyde with a secondary piperazine nitrogen on a benzene ring, giving two orthogonal reactive handles for organic synthesis. Tech Serve Solutions supplies it as a research-grade reagent for use in medicinal chemistry and the preparation of piperazine-containing intermediates and fine chemicals.
- IUPAC
- 3-(Piperazin-1-yl)benzaldehyde
- Synonyms
- 1-(3-Formylphenyl)piperazine3-(Piperazin-1-yl)benzaldehyde3-(1-Piperazinyl)benzaldehyde3-Piperazin-1-yl-benzaldehyde
Heterocyclic building block
Serves as a versatile scaffold in chemical synthesis, pairing a piperazine ring with a meta-substituted benzaldehyde. It is used to assemble more elaborate piperazine derivatives and substituted aromatic structures.
Aldehyde-directed transformations
The formyl group undergoes standard carbonyl chemistry such as reductive amination, condensation to imines and Schiff bases, and reduction to the corresponding alcohol, enabling rapid elaboration of the aromatic core.
Piperazine functionalisation
The free secondary amine of the piperazine ring can be acylated, alkylated, sulfonylated or arylated, providing a convenient point of diversification when constructing target molecules.
Medicinal-chemistry intermediate
Piperazine and benzaldehyde motifs are common in pharmaceutical research, so this dual-functional reagent is well suited to library synthesis and structure-activity studies. Specific end uses depend on the customer's programme.
Laboratory and research reagent
Used in research and development laboratories as a defined organic intermediate for method development and small-scale synthesis.
| Molecular weight | 190.24 |
|---|---|
| Empirical formula | C11H14N2O |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Formylphenyl)piperazine used for?
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It is used mainly as a bifunctional building block in organic and medicinal chemistry. The aldehyde and the secondary piperazine nitrogen act as independent reactive sites, allowing the molecule to be elaborated into a range of piperazine-bearing intermediates and fine chemicals.
What is the CAS number and molecular formula of 1-(3-Formylphenyl)piperazine?
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The CAS number is 870703-56-3 and the molecular formula is C11H14N2O, with a molecular weight of 190.24 g/mol. Its MDL number is MFCD07369775. It is also known as 3-(piperazin-1-yl)benzaldehyde.
What grade and purity does Tech Serve Solutions supply?
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We supply 1-(3-Formylphenyl)piperazine as a research-grade reagent suitable for synthesis and laboratory use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification and certificate of analysis with the exact assay are provided on request for each batch.
What are the safety and handling requirements?
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It is classified under GHS with signal word Warning (pictogram GHS07). The hazard statements are H302 (harmful if swallowed), H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and consult the SDS before use. Refer to the safety data sheet for full guidance.
How is 1-(3-Formylphenyl)piperazine packed, shipped and exported?
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It is packed in tightly sealed, appropriately labelled containers sized to the order, from gram quantities to bulk. As an experienced global exporter, Tech Serve Solutions arranges compliant international shipping with full documentation, including the SDS and certificate of analysis.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packing preference and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged for evaluation where appropriate.
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