1-(3-Fluorophenyl)biguanide hydrochloride
1-(3-Fluorophenyl)biguanide hydrochloride (CAS 2267-49-4) is an arylbiguanide salt with the formula C8H11ClFN5 (C8H10FN5 . HCl) and a molar mass of 231.66 g/mol. The hydrochloride salt of 1-(3-fluorophenyl)biguanide, it is a crystalline solid melting near 231-235 C. It serves chiefly as an organic building block and guanidine reagent in chemical synthesis. Tech Serve Solutions supplies it as a research-grade reagent for laboratory and intermediate use.
- Synonyms
- 1-(3-Fluorophenyl)biguanide hydrochloride1-(3-Fluorophenyl)biguanide HClN-(3-Fluorophenyl)imidodicarbonimidic diamide hydrochloride3-Fluorophenylbiguanide hydrochlorideCAS 2267-49-4
Organic building block
Used as a fluorinated arylbiguanide building block in multi-step organic synthesis. The reactive biguanide unit and the 3-fluorophenyl group allow it to be incorporated into more complex nitrogen-rich molecules.
Heterocyclic synthesis
Biguanides such as this are established precursors to nitrogen heterocycles, condensing with carbonyl and other electrophilic partners. It is commonly employed to construct triazine and related ring systems.
Guanidine reagent
As a substituted guanidine reagent it provides a strongly basic, nucleophilic nitrogen framework for condensation and cyclisation reactions in the laboratory.
Pharmaceutical and research intermediate
Supplied as a research-grade intermediate for discovery and development chemistry. Suitability for any specific route should be confirmed by the user against their own process and quality requirements.
| Molecular weight | 231.66 |
|---|---|
| Linear formula | FC6H4NHC=NHNHC=NHNH2 · HCl |
| Assay | 97% |
| Melting point | 231-235 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Fluorophenyl)biguanide hydrochloride used for?
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It is used primarily as an organic building block and guanidine reagent in chemical synthesis, including the preparation of nitrogen heterocycles such as triazine systems. It is handled as a research-grade intermediate rather than a finished product.
What is the CAS number and molecular formula of 1-(3-Fluorophenyl)biguanide hydrochloride?
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The CAS number is 2267-49-4. The molecular formula of the salt is C8H11ClFN5 (the free base C8H10FN5 combined with HCl), with a molecular weight of 231.66 g/mol. The MDL number is MFCD00203529.
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a research/technical-grade reagent with a typical assay of 97%. We do not represent this material as USP, BP or EP pharmacopoeial grade. A certificate of analysis can be provided with each batch on request.
How should 1-(3-Fluorophenyl)biguanide hydrochloride be handled and stored?
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Handle with appropriate laboratory controls: wear eye protection and gloves, and use a suitable particulate respirator (N95/P1) where dust may be generated. It is classified WGK 3 (highly hazardous to water in Germany), so prevent release to drains and the environment. Always consult the current Safety Data Sheet before use.
How is 1-(3-Fluorophenyl)biguanide hydrochloride packed, shipped and exported?
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It is packed as a dry crystalline solid in sealed containers sized to the order, from laboratory quantities upward, with full labelling and documentation. Tech Serve Solutions exports worldwide and prepares shipments in line with the applicable transport and customs requirements for the destination.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged where appropriate for evaluation.
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