1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane
1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane (CAS 7453-26-1) is an organosilicon compound with the molecular formula [CH3Si(C6H5)2]2NH and a molecular weight of 409.67 g/mol. This disilazane derivative finds utility as a silylation reagent in chemical synthesis and analytical applications, particularly for derivatization in gas chromatography. Its structure, featuring two phenyl-substituted silicon atoms linked by a nitrogen atom, imparts specific reactivity for modifying hydroxyl and amino groups.
- IUPAC
- 1,1,3,3-Tetraphenyl-1,3-dimethyldisilazane,TPDMDS
- Synonyms
- 3,3-tetraphenyldisilazane[CH3Si(C6H5)2]2NH1,1,3,3-Tetraphenyl-1,3-dimethyldisilazaneTPD MDS
![1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane ([CH3Si(C6H5)2]2NH) — chemical structure, CAS 7453-26-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F7453-26-1.png&w=3840&q=75)
Silylation Reagent
This compound serves as an effective silylation reagent. It is employed to introduce silyl groups onto various molecules, altering their physical and chemical properties for further reactions or analysis.
Gas Chromatography Derivatization
1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane is used as a derivatization reagent for gas chromatography (GC). It reacts with analytes to form more volatile and thermally stable derivatives, improving their detection and separation.
Chemical Synthesis
In chemical synthesis, it acts as a building block or reagent for creating complex organosilicon structures. Its specific reactivity can be harnessed in multi-step synthetic pathways.
Analytical Chemistry
As an analytical reagent, it is valuable for modifying compounds to enhance their detectability or chromatographic behaviour, aiding in qualitative and quantitative analysis.
| Molecular weight | 409.67 |
|---|---|
| Linear formula | [CH3Si(C6H5)2]2NH |
| Assay | ≥98.0% (NT) |
| Melting point | 87-89 °C(lit.)87-89 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane used for?
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This compound is primarily used as a silylation reagent in chemical synthesis and for derivatization in gas chromatography to improve the volatility and stability of analytes.
What are the CAS number and formula for 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane?
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The CAS number is 7453-26-1 and the linear formula is [CH3Si(C6H5)2]2NH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥98.0% (NT). We do not represent this product as USP, BP, or EP grade.
How should 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane be handled?
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This compound is classified as irritating to the skin, eyes, and respiratory system (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane a controlled substance?
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The provided data does not indicate that 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane is a controlled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific shipping and export details are provided upon inquiry.
How can I request a sample or quote?
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Please contact our sales team through the website or by phone to request a sample or a formal quotation for 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane.
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