1,3-Bis(diphenylphosphino)propane
1,3-Bis(diphenylphosphino)propane (CAS 6737-42-4), with the linear formula (C₆H₅)₂PCH₂CH₂CH₂P(C₆H₅)₂, is a white crystalline solid possessing a molecular weight of 412.44 g/mol. This bidentate phosphine ligand is a crucial component in homogeneous catalysis, frequently employed in various coupling reactions and carbonylations. Its specific chelating properties make it valuable in synthetic organic and organometallic chemistry for facilitating complex transformations.
- IUPAC
- dppp
- Synonyms
- (C6H5)2PCH2CH2CH2P(C6H5)2dppp
Catalysis in C-C Bond Formation
1,3-Bis(diphenylphosphino)propane acts as a vital ligand in transition metal-catalysed reactions for forming carbon-carbon bonds. It is instrumental in processes such as Suzuki-Miyaura, Negishi, and Sonogashira coupling reactions, enabling the synthesis of complex organic molecules.
Ligand in Carbonylation Reactions
This phosphine ligand is utilised in carbonylation processes, where carbon monoxide is incorporated into organic molecules. It assists in stabilising catalytic intermediates and influencing the selectivity and efficiency of these important synthetic transformations.
Organometallic Chemistry Research
Due to its chelating ability and electronic properties, 1,3-Bis(diphenylphosphino)propane is a common reagent in organometallic chemistry research. It is used to synthesise and study novel metal complexes with potential catalytic applications.
| Molecular weight | 412.44 |
|---|---|
| Linear formula | (C6H5)2PCH2CH2CH2P(C6H5)2 |
| Assay | 97% |
| Melting point | 63-65 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Ligand For | C-C Bond FormationCarbonylationsNegishi CouplingSonogashira CouplingSuzuki-Miyaura Coupling |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Bis(diphenylphosphino)propane used for?
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1,3-Bis(diphenylphosphino)propane is primarily used as a bidentate phosphine ligand in homogeneous catalysis, particularly for C-C bond formation reactions like Suzuki-Miyaura, Negishi, and Sonogashira couplings, as well as in carbonylation reactions.
What are the CAS number and formula for 1,3-Bis(diphenylphosphino)propane?
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The CAS number is 6737-42-4, and its linear formula is (C₆H₅)₂PCH₂CH₂CH₂P(C₆H₅)₂.
What grade and purity does Tech Serve Solutions supply for 1,3-Bis(diphenylphosphino)propane?
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Tech Serve Solutions supplies 1,3-Bis(diphenylphosphino)propane with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 1,3-Bis(diphenylphosphino)propane be handled?
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This compound is classified as a Warning with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). It requires appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
Is 1,3-Bis(diphenylphosphino)propane a controlled substance?
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The provided data does not indicate that 1,3-Bis(diphenylphosphino)propane is a controlled substance.
How is 1,3-Bis(diphenylphosphino)propane packed and shipped?
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Tech Serve Solutions is a global supplier and exporter of chemicals and adheres to all relevant regulations for packing and shipping. Specific details for international export are available upon request.
How can I request a sample or quote for 1,3-Bis(diphenylphosphino)propane?
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To request a sample or quote, please use the contact form on our website or reach out to our sales department directly, referencing product code 6737-42-4.
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