1,2-Phenylenediamine
1,2-Phenylenediamine (CAS 95-54-5), also known as o-Phenylenediamine (OPD), is an aromatic amine with the chemical formula C6H4(NH2)2 and a molecular weight of 108.14 g/mol. Supplied by Tech Serve Solutions as zone-refined with an assay of ≥99%, this compound is a crucial building block and reagent in organic synthesis. It is widely employed in the production of heterocyclic compounds, dyes, and pharmaceuticals, and also serves as a derivatization agent.
- IUPAC
- 1,2-Diaminobenzene,o-Phenylenediamine,OPD
- Synonyms
- 1,2-Diaminobenzeneo-PhenylenediamineOPD
Synthesis of Heterocyclic Compounds
1,2-Phenylenediamine is a key precursor for synthesizing various heterocyclic systems, including benzimidazoles and quinoxalines, which are important scaffolds in medicinal chemistry and materials science.
Reagent in Analytical Chemistry
It is utilized as a derivatization agent, particularly for the detection and quantification of dicarbonyl compounds and selenium through spectrophotometric or fluorometric methods.
Precursor for Dyes and Pigments
The compound serves as an intermediate in the manufacture of certain dyes and pigments, contributing to their colouristic properties and stability.
Biochemical Research
In biochemical applications, 1,2-Phenylenediamine is used as a substrate for enzymes like peroxidases and as a reagent in diagnostic assays.
| Molecular weight | 108.14 |
|---|---|
| Linear formula | C6H4(NH2)2 |
| Assay | ≥99% |
| Grade | zone-refined |
| Boiling point | 256-258 °C(lit.) |
| Solubility | H2O: soluble1 tablet/10 mL, clear, colorless |
| Concentration | 20 mg/tablet (~45 mg) |
| Melting point | 100-102 °C(lit.) |
| Vapour pressure | 0.01 mmHg (25 °C) |
| Vapour density | 3.7 (vs air) |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H341Suspected of causing genetic defects
- H351Suspected of causing cancer
- H371May cause damage to organs
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Flash point | 136 °C / 276.8 °F |
|---|---|
| Transport (UN / ADR) | UN 1673 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 20/21-25-36-40-43-50/53-68 |
| Safety statements (S) | 28-36/37-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Purified By | sublimation |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Phenylenediamine used for?
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1,2-Phenylenediamine (CAS 95-54-5) is used as a building block in organic synthesis for creating heterocyclic compounds like benzimidazoles and quinoxalines, as a derivatization agent in analytical chemistry, and in the production of dyes and pigments.
What is the CAS number and chemical formula for 1,2-Phenylenediamine?
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The CAS number for 1,2-Phenylenediamine is 95-54-5 and its linear chemical formula is C6H4(NH2)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Phenylenediamine in a zone-refined grade with an assay of ≥99%. TSS does not represent this product as USP, BP, or EP grade.
How should 1,2-Phenylenediamine be handled safely?
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1,2-Phenylenediamine is classified as Danger, with hazards including acute toxicity (oral, dermal, inhalation), skin sensitisation, serious eye irritation, mutagenicity, carcinogenicity, and specific target organ toxicity. It is also very toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment (PPE) in a well-ventilated area, and avoid release to the environment.
How is 1,2-Phenylenediamine packed, shipped, and exported?
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1,2-Phenylenediamine is packaged according to international shipping regulations for hazardous materials. Tech Serve Solutions, as a global supplier, can export this chemical worldwide, adhering to all relevant compliance requirements.
How can I request a quote or sample of 1,2-Phenylenediamine?
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To request a quote or a sample of 1,2-Phenylenediamine, please contact the Tech Serve Solutions sales team via our website or direct inquiry.
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