1,2-Naphthoquinone-4-sulfonic acid sodium salt
1,2-Naphthoquinone-4-sulfonic acid sodium salt (CAS: 521-24-4), with a molecular weight of 260.20, is a chemical compound utilized as Folin's reagent. It serves a primary role in analytical chemistry, particularly in colorimetric assays. Its properties make it suitable for specific detection methods in pharmaceutical analysis, contributing to quality control processes.
- IUPAC
- 3,4-Dihydro-3,4-dioxo-1-naphthalenesulfonic acid sodium salt,Folin’s reagent,Sodium 1,2-naphthoquinone-4-sulfonate
- Synonyms
- 3,4-Dihydro-3,4-dioxo-1-naphthalenesulfonic acid sodium saltFolin’s reagentSodium 1,2-naphthoquinone-4-sulfonate
Colorimetric Assay Reagent
This compound, known as Folin's reagent, is employed in colorimetric assays for the quantitative determination of specific substances. Its application is documented in the analysis of procaine hydrochloride within pharmaceutical preparations.
Pharmaceutical Analysis
As a reagent in analytical chemistry, it facilitates the precise measurement of active pharmaceutical ingredients. This aids in ensuring the quality and consistency of pharmaceutical products during manufacturing and quality control.
Organic Synthesis
Recognized as an organic building block, this sulfonic acid derivative can potentially be used in various chemical synthesis pathways. Its structure lends itself to further functionalization in organic chemistry research.
| Molecular weight | 260.20 |
|---|---|
| Empirical formula | C10H5NaO5S |
| Assay | 97% |
| Solubility | alcohol: slightly soluble95%acetone: moderately soluble(lit.)benzene: insoluble(lit.)carbon disulfide: insoluble(lit.)chloroform: insoluble(lit.)diethyl ether: insoluble(lit.)petroleum ether: insoluble(lit.)water: soluble(lit.) |
| Application | 1,2-Naphthoquinone-4-sulfonic acid sodium salt (Folin′s reagent) was used in the colorimetric assay for determination of procaine hydrochloride in pharmaceutical preparations1. |
| Melting point | 289 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Naphthoquinone-4-sulfonic acid sodium salt used for?
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It is primarily used as Folin's reagent in colorimetric assays for determining substances such as procaine hydrochloride in pharmaceutical preparations. It also serves as an organic building block in chemical synthesis.
What is the CAS number and formula for 1,2-Naphthoquinone-4-sulfonic acid sodium salt?
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The CAS number is 521-24-4. The empirical formula is C10H5NaO5S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Naphthoquinone-4-sulfonic acid sodium salt with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling requirements for this chemical?
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This compound is a warning substance with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95, eyeshields, and gloves. Handle in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions carefully packs and handles chemicals for safe transit, adhering to international shipping regulations. We are experienced global suppliers and exporters of fine chemicals.
How can I request a sample or a quote?
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To request a sample or a quote for 1,2-Naphthoquinone-4-sulfonic acid sodium salt, please contact our sales team via the website or direct email.
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