1-(2-Methoxyethyl)piperazine
1-(2-Methoxyethyl)piperazine (CAS 13484-40-7) is a mono-substituted piperazine building block with the molecular formula C7H16N2O and a molar mass of 144.21 g/mol. Supplied as a liquid, it carries one free secondary amine alongside a methoxyethyl side chain, making it a versatile reactant for chemical synthesis. It is used chiefly as an intermediate in preparing biologically and pharmacologically active molecules. Tech Serve Solutions supplies it for research and manufacturing.
- IUPAC
- 4-(2-Methoxyethyl)piperazine,N-(2-Methoxyethyl)piperazine
- Synonyms
- 1-(2-Methoxyethyl)piperazine4-(2-Methoxyethyl)piperazineN-(2-Methoxyethyl)piperazine2-(Piperazin-1-yl)ethyl methyl ether
Pharmaceutical intermediate
Serves as a reactant in the preparation of biologically and pharmacologically active molecules. The piperazine ring is a recurring motif in medicinal chemistry, and this derivative offers a pre-installed methoxyethyl substituent.
Heterocyclic building block
Used as a C4-to-C8 heterocyclic building block in multi-step organic synthesis. Its free secondary amine provides a reactive site for acylation, alkylation, reductive amination and related transformations.
Fine and custom chemical synthesis
Applied in fine-chemical and custom synthesis routes that require a mono-functionalised piperazine scaffold. The methoxyethyl group can modulate the polarity and solubility of target compounds.
Laboratory reagent
Functions as a research-grade reagent for exploratory and route-development chemistry where a substituted piperazine amine is needed.
| Molecular weight | 144.21 |
|---|---|
| Empirical formula | C7H16N2O |
| Assay | 97% |
| Boiling point | 193-194 °C(lit.) |
| Density | 0.970 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4730(lit.) |
| Application | Reactant for:• Preparation of biologically and pharmacologically active molecules1,2,3,4,5 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Transport (UN / ADR) | UN 2735 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(2-Methoxyethyl)piperazine used for?
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It is used mainly as a reactant and intermediate in the preparation of biologically and pharmacologically active molecules. As a mono-substituted piperazine building block, it supports chemical synthesis through reactions at its free secondary amine, such as acylation, alkylation and reductive amination.
What is the CAS number and molecular formula of 1-(2-Methoxyethyl)piperazine?
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The CAS number is 13484-40-7 and the molecular formula is C7H16N2O, with a molecular weight of 144.21 g/mol. The MDL number is MFCD00191214 and the Beilstein registry number is 105098.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(2-Methoxyethyl)piperazine at a typical assay of 97% as a research and technical grade for synthesis and laboratory use. We do not represent it as USP, BP or EP pharmacopoeial grade. A Certificate of Analysis accompanies each batch.
What are the safety and handling precautions for 1-(2-Methoxyethyl)piperazine?
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It is classified as corrosive under GHS (pictogram GHS05, signal word Danger, hazard statement H314: causes severe skin burns and eye damage). Handle it with gloves, goggles and a face shield, use appropriate respiratory protection, and avoid contact with skin and eyes. In case of skin or eye contact, rinse thoroughly with water and seek medical attention. Always consult the Safety Data Sheet before use.
How is 1-(2-Methoxyethyl)piperazine packed, shipped and exported?
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It is packed in suitable corrosion-compatible containers and labelled in line with GHS requirements. For transport it is classified as UN 2735, Class 8 (corrosive), Packing Group III. Tech Serve Solutions arranges export with the required dangerous-goods documentation and ships globally; pack sizes can be tailored to laboratory or bulk requirements.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and documentation. Samples and a Certificate of Analysis can be provided on request.
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