1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrasodium salt
1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrasodium salt (CAS: 126824-24-6) is a chelating agent with the molecular formula C22H20N2Na4O10 and a molecular weight of 564.36 g/mol. This compound is primarily utilised as a calcium ion (Ca <sup>2+</sup>) indicator, exhibiting fluorescence that is suppressed by calcium. Its solubility in water makes it suitable for various biochemical and research applications.
- IUPAC
- 1,2-Bis (2-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid tetrasodium salt,BAPTA-Na4,Tetrasodium 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetate
- Synonyms
- Tetrasodium 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetateBAPTA-Na41,2-Bis (2-aminophenoxy) ethane-N,N,N′,N′-tetraacetic acid tetrasodium salt

Calcium Ion Indicator
This tetrasodium salt functions as a sensitive indicator for calcium ions (Ca <sup>2+</sup>) in solution. Its fluorescence properties are modulated by the presence of calcium, allowing for its detection and quantification in biological and chemical assays.
Biochemical Research
Utilised in biochemical and reagent applications, this compound serves as a valuable tool for researchers studying cellular processes involving calcium ions. Its properties lend themselves to use in flow cytometry and microscopy.
Fluorescent Probes
As a fluorescent indicator and probe, it can be employed in various detection methods. The compound exhibits specific excitation and emission wavelengths that are influenced by calcium binding.
| Molecular weight | 564.36 |
|---|---|
| Empirical formula | C22H20N2Na4O10 |
| Assay | ≥95% (HPLC) |
| Solubility | H2O: soluble10 mg/mL, clear, faintly yellow |
| Storage temperature | −20°C |
| Impurities tested | ≤12.5% water |
| Application | suitable as Ca2+-indicator (fluorescence suppressed by Ca2+) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 254 nm; λem 363 nm in H2Oλex 274 nm; λem 363 nm (with calcium) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrasodium salt used for?
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This compound is primarily used as a calcium ion (Ca <sup>2+</sup>) indicator in biochemical and research applications. Its fluorescence is suppressed by calcium, enabling its use in various detection methods, including flow cytometry and microscopy.
What are the CAS number and molecular formula?
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The CAS number is 126824-24-6, and the empirical formula (Hill notation) is C22H20N2Na4O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥95% (HPLC). It may contain up to 12.5% water. We do not represent this product as USP, BP, or EP grade.
How should this chemical be handled safely?
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When handling, appropriate personal protective equipment should be used, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The WGK Germany classification is 3, indicating a high hazard to water.
How is the product shipped and stored?
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The product should be stored at -20°C. Tech Serve Solutions ensures secure and compliant packaging and export of this chemical globally.
How can I request a sample or quote?
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To request a sample or a quote for 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrasodium salt, please contact our sales team via the website or your dedicated account manager.
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