1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole

CAS 50257-40-4C18H26N2O2SChemical Synthesis

1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole (CAS: 50257-40-4), with the molecular formula C18H26N2O2S and a molecular weight of 334.48 g/mol, is a key chemical intermediate. It functions primarily as a coupling or condensing agent, particularly valuable in the synthesis of oligonucleotides. Its robust chemical structure makes it suitable for complex organic synthesis applications where precise control over bond formation is required.

IUPAC: 1-(2,4,6-Triisopropylphenylsulfonyl)imidazole,TPSI
Synonyms: 50257-40-4, C18H26N2O2S, 1-(2,4,6-Triisopropylphenylsulfonyl)imidazole, TPSI

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1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole (C18H26N2O2S) — chemical structure, CAS 50257-40-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksC9 to C30+Chemical SynthesisHeterocyclic Building BlocksImidazoles

01 /Applications

Oligonucleotide Synthesis

This compound serves as an effective coupling or condensing agent in the intricate process of oligonucleotide synthesis, facilitating the formation of phosphodiester bonds.

Chemical Synthesis Reagent

As a specialized building block, it is employed in various chemical synthesis pathways. Its structure lends itself to complex organic transformations and the construction of sophisticated molecular architectures.

Heterocyclic Chemistry

Utilised within heterocyclic building block chemistry, this imidazole derivative can be incorporated into diverse molecular structures, offering versatility for synthetic chemists.

02 /Properties

Molecular weight	334.48
Empirical formula	C18H26N2O2S
Assay	99%
Application	Coupling or condensing agent in oligonucleotide synthesis.
Melting point	118-120 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

50257-40-4

MDL number

MFCD00005283

PubChem substance

24854658

Beilstein registry

962743

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole used for?

1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole is primarily used as a coupling or condensing agent in oligonucleotide synthesis.

What is the CAS number and molecular formula for 1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole?

The CAS number is 50257-40-4, and the molecular formula is C18H26N2O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole with an assay of 99%. This product is supplied for research and development purposes and is not intended for USP, BP, EP, or other pharmacopoeia applications unless explicitly stated.

How should 1-(2,4,6-Triisopropylbenzenesulfonyl)imidazole be handled?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK 2 in Germany, indicating a higher hazard level.