1,1′-(Azodicarbonyl)dipiperidine
1,1′-(Azodicarbonyl)dipiperidine (CAS: 10465-81-3) is a chemical compound with the molecular formula C12H20N4O2 and a molecular weight of 252.31 g/mol. It is primarily utilised as a synthetic reagent, particularly in studies involving C-X bond formation. Its applications are rooted in its role as a key component in various chemical synthesis pathways and reactions like the Mitsunobu reaction.
- IUPAC
- 1,1′-Azobis(N,N-pentamethyleneformamide),ADD,Azodicarboxylic acid dipiperidide,NSC 356027,SR 4077
- Synonyms
- C12H20N4O21,1′-Azobis(N,N-pentamethyleneformamide)ADDAzodicarboxylic acid dipiperidideNSC 356027SR 4077

C-X Bond Formation
This compound serves as a valuable reagent in the synthesis of C-X bonds, a fundamental transformation in organic chemistry. It facilitates reactions leading to various substituted organic molecules.
Mitsunobu Reaction Reagent
1,1′-(Azodicarbonyl)dipiperidine is employed in synthetic strategies that utilise the Mitsunobu reaction. This application allows for stereospecific synthesis and functional group interconversions.
Synthesis of Aryl-Substituted Hydrazides
It is used in copper-catalyzed addition reactions of boronic acids to azodicarboxyl derivatives, leading to the formation of aryl-substituted hydrazides.
Chemical Synthesis
As a versatile building block, it finds application in diverse organic synthesis protocols, enabling the construction of complex molecular architectures.
| Molecular weight | 252.31 |
|---|---|
| Empirical formula | C12H20N4O2 |
| Assay | 99% |
| Application | Used in a study of the copper-catalyzed addition of aryboronic acids to azodicarboxyl derivatives providing aryl-substituted hydrazides.10 |
| Melting point | 134-136 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1′-(Azodicarbonyl)dipiperidine used for?
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1,1′-(Azodicarbonyl)dipiperidine is used in chemical synthesis, particularly for C-X bond formation and in reactions like the Mitsunobu reaction. It is also utilised in the synthesis of aryl-substituted hydrazides.
What is the CAS number and formula for 1,1′-(Azodicarbonyl)dipiperidine?
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The CAS number is 10465-81-3, and the molecular formula is C12H20N4O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,1′-(Azodicarbonyl)dipiperidine with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 1,1′-(Azodicarbonyl)dipiperidine be handled?
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According to GHS, this compound is a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask (N95), eyeshields, and gloves. Handle in a well-ventilated area.
Is 1,1′-(Azodicarbonyl)dipiperidine exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1,1′-(Azodicarbonyl)dipiperidine.
How can I request a sample or quote for 1,1′-(Azodicarbonyl)dipiperidine?
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To request a sample or quote, please contact our sales team through the website or by phone. Please specify the CAS number 10465-81-3.
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