1-(1,3-Dioxolan-2-ylmethyl)piperazine
1-(1,3-Dioxolan-2-ylmethyl)piperazine (CAS: 682802-92-2) is a heterocyclic organic compound with the molecular formula C8H16N2O2 and a molecular weight of 172.22 g/mL. It functions as a valuable building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. Its structure, featuring a piperazine ring linked to a dioxolane moiety, makes it suitable for constructing more complex molecules in research and development settings.
- IUPAC
- 2-(Piperazinomethyl)-1,3-dioxolane,Piperazinoacetaldehyde ethylene acetal
- Synonyms
- C8H16N2O22-(Piperazinomethyl)-1,3-dioxolanePiperazinoacetaldehyde ethylene acetal

Chemical Synthesis
This compound serves as a versatile intermediate in organic synthesis. Its functional groups allow for further chemical modifications, enabling the creation of novel molecular architectures for various research purposes.
Heterocyclic Chemistry
As a piperazine derivative, it is particularly useful in the synthesis of complex heterocyclic systems. These systems are often explored for their potential applications in medicinal chemistry and material science.
Research and Development
1-(1,3-Dioxolan-2-ylmethyl)piperazine is utilized in R&D laboratories for the exploration of new chemical entities. Its availability as a building block supports academic and industrial research efforts in discovering compounds with specific properties.
| Molecular weight | 172.22 |
|---|---|
| Empirical formula | C8H16N2O2 |
| Assay | ≥97.0% |
| Density | 1.492 g/mL at 20 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(1,3-Dioxolan-2-ylmethyl)piperazine used for?
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1-(1,3-Dioxolan-2-ylmethyl)piperazine is primarily used as a building block in chemical synthesis, particularly in the field of heterocyclic chemistry, supporting research and development activities.
What are the CAS number and molecular formula for this compound?
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The CAS number for 1-(1,3-Dioxolan-2-ylmethyl)piperazine is 682802-92-2, and its molecular formula is C8H16N2O2. The empirical formula in Hill notation is C8H16N2O2, and its molecular weight is 172.22 g/mL.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(1,3-Dioxolan-2-ylmethyl)piperazine with an assay of ≥97.0%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should 1-(1,3-Dioxolan-2-ylmethyl)piperazine be handled safely?
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This compound is classified as a Warning, with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory tract irritation (H335). Appropriate personal protective equipment such as eyeshields, gloves, and a suitable respirator cartridge should be used. Avoid breathing dust/fume/gas/mist/vapours/spray and ensure adequate ventilation.
Is 1-(1,3-Dioxolan-2-ylmethyl)piperazine a controlled substance?
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The provided safety data does not indicate that 1-(1,3-Dioxolan-2-ylmethyl)piperazine is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions offers global export of chemicals. Specific packing and shipping details are available upon request and are handled in compliance with international regulations.
How can I request a sample or quote for 1-(1,3-Dioxolan-2-ylmethyl)piperazine?
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To request a sample or a quotation, please contact our sales department through the provided contact information on our website, referencing the product name and CAS number.
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